Strattera Atomoxetine HCl: Side Effects, Uses, Dosage, Interactions, Warnings

13/01/2025  |   Sober living  

Serious side effects from Strattera can occur, but they’re is straterra a stimulant not common. If you have serious side effects from Strattera, call your doctor right away. But if you think you’re having a medical emergency, call 911 or your local emergency number. Here’s a list of some of the mild side effects that Strattera can cause. To learn about other mild side effects, talk with your doctor or pharmacist, or read Strattera’s prescribing information.

Poor metabolizers (PMs) of CYP2D6 have a 10-fold higher AUC and a 5-fold higher peak concentration to a given dose of STRATTERA compared with extensive metabolizers (EMs). The blood levels in PMs are similar to those attained by taking strong inhibitors of CYP2D6. The higher blood levels in PMs lead to a higher rate of some adverse effects of STRATTERA see ADVERSE REACTIONS.

Some people have thoughts about suicide while taking Strattera. Stay alert to changes in mood or symptoms, especially in children and teenagers, particularly early on in treatment or during dose adjustments. Report any sudden or severe changes to their healthcare provider immediately. When starting or switching to Adderall XR, your healthcare provider may start with 10 milligrams (children and adolescents) or 20 milligrams (adults) once daily and adjust the dosage weekly as needed. You can take the capsules whole or sprinkle its contents on applesauce, but it should be consumed immediately. Strattera is a prescription medication that selectively inhibits the reuptake (reabsorption) of norepinephrine to enhance attention and reduce impulsiveness and hyperactivity in ADHD.

  • One author (Dr. Monk) screened the title and abstracts for possible full text review, using prespecified inclusion and exclusion criteria.
  • If the first drug you take doesn’t help enough or causes too many side effects, they can switch you to a different one.
  • In children, the dosage of Strattera depends on the child’s body weight in kilograms (kg).
  • However, be sure to take the dosage your doctor prescribes for you.
  • When stimulant medications are prescribed at appropriate doses and taken as prescribed, the risk of potential addiction is low.

Serious side effects

Unless otherwise specified, these adverse reactions have occurred in adults and children and adolescents. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Adderall is a prescription stimulant medication used to improve attention and reduce impulsiveness and hyperactivity in people diagnosed with ADHD. Like Strattera, it is approved for use in adults and children 6 and older. Atomoxetine is from a group of medicines called selective norepinephrine reuptake inhibitors (SNRI). Strattera, the original brand of atomoxetine, received FDA approval on November 26, 2002, for the treatment of Attention-Deficit/Hyperactivity Disorder.

  • Psychopharmacological treatment for ADHD includes stimulant or, if warranted, nonstimulant (e.g., atomoxetine, bupropion, clonidine, guanfacine) medications (Pliszka et al. 2006; National Institute for Health and Clinical Excellence 2008; Seixas et al. 2012).
  • But many people began to notice symptom improvement within 4 weeks.
  • Following oral administration of atomoxetine to PMs, mean apparent plasma clearance is 0.03 L/hr/kg and mean half-life is 21.6 hours.
  • Stay alert to changes in your mood or symptoms, especially if you have ever had suicidal thoughts.
  • Strattera may also cause severe liver injury, new or worsening psychosis, aggressive behavior, and erections lasting more than four hours.

While Strattera takes a while to kick in compared to Ritalin, the effects last longer once the drug builds up in your body. A daily dose of Strattera should work 24 hours as long as you take the drug around the same time every day. Ritalin is the brand name of a stimulant drug called methylphenidate.

Effects On Urine Outflow From The Bladder

Of the 413 patients who completed the double-blind placebo lead-in, 149 (36.1%) patients discontinued the study. There have been postmarketing reports of anxiety see ADVERSE REACTIONS. The pharmacokinetics of atomoxetine in children and adolescents are similar to those in adults. The safety, efficacy, and pharmacokinetics of STRATTERA in pediatric patients less than 6 years of age have not been evaluated. The following adverse reactions have been identified during post approval use of STRATTERA.

Rats were treated with 1, 10, or 50 mg/kg/day (approximately 0.2, 2, and 8 times, respectively, the maximum human dose on a mg/m2 basis) of atomoxetine given by gavage from the early postnatal period (Day 10 of age) through adulthood. A slight delay in onset of incisor eruption was seen at 50 mg/kg. A slight increase in motor activity was seen on Day 15 (males at 10 and 50 mg/kg and females at 50 mg/kg) and on Day 30 (females at 50 mg/kg) but not on Day 60 of age.

Strattera precautions

Some pharmacies offer labels that have large print, braille, or a code you scan with a smartphone to convert text to speech. If your local pharmacy doesn’t have these options, your doctor or pharmacist may be able to direct you to one that does. You may wonder how Strattera compares with other medications that are prescribed for similar uses. To find out how Strattera and Vyvanse are alike and different, see this article.

Atomoxetine (Strattera) – Uses, Side Effects, and More

Once therapeutic levels have been reached, the effects of the medication last 24 hours. Strattera is a norepinephrine reuptake inhibitor, which means it allows the neurotransmitter norepinephrine to be available to the brain’s neurons for longer. Avoid coming in contact with an open or a broken atomoxetine capsule. Wash any surfaces that an open capsule touches, such as your hands. If you or your child gets any powder from the atomoxetine capsules in the eye, rinse well with water and call your healthcare provider right away.

Rats were treated with up to approximately 50 mg/kg/day of atomoxetine (approximately 6 times the MRHD on a mg/m2 basis) in the diet from 2 weeks (females) or 10 weeks (males) prior to mating through the periods of organogenesis and lactation. In 1 of 2 studies, decreases in pup weight and pup survival were observed. The decreased pup survival was also seen at 25 mg/kg (but not at 13 mg/kg). Data on the long-term effects of STRATTERA on growth come from open-label studies, and weight and height changes are compared to normative population data. In general, the weight and height gain of pediatric patients treated with STRATTERA lags behind that predicted by normative population data for about the first 9-12 months of treatment.

In addition, identifying patient characteristics or factors that may help physicians tailor treatment regimens has, to date, been mostly unsuccessful (Quintana et al. 2007). Safety and tolerability outcomes for stimulant and atomoxetine combination therapy were reported in the three prospective studies and three of the seven retrospective studies of patients with ADHD (Table 4). Safety and tolerability outcomes reported in the prospective studies were adverse events, changes in blood pressure and pulse and heart rates (Carlson et al. 2007; Quintana et al. 2007; Hammerness et al. 2009). Findings on ECG parameters (Quintana et al. 2007; Hammerness et al. 2009) and blood chemistry (Hammerness et al. 2009) were also reported in some of these studies. No serious adverse events were reported in these studies; however, 10 patients discontinued because of treatment-related adverse events (Carlson et al. 2007; Quintana et al. 2007; Hammerness et al. 2009) (Table 4). There were also two clinically significant changes in ECG parameters (RR interval Qunitana et al. 2007 and PR Hammerness et al. 2009) (Table 4).

Atomoxetine has not been studied in children less than 6 years old. Strattera is now available as a generic under the active ingredient name atomoxetine. Atomoxetine is an SNRI medicine used to treat attention deficit hyperactivity disorder (ADHD) to help improve attention and reduce hyperactivity and impulsiveness. Atomoxetine is thought to work by selectively blocking a protein (pre-synaptic norepinephrine transporter) that affects chemicals in the brain and nerves involved in hyperactivity and impulse control; blocking this protein may improve ADHD symptoms. Atomoxetine is usually used together with psychological, educational, and social measures.



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